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Biosynthesis [electronic resource] : Aromatic Polyketides, Isoprenoids, Alkaloids

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Biosynthesis [electronic resource] : Aromatic Polyketides, Isoprenoids, Alkaloids
Original Title Biosynthesis [electronic resource] : Aromatic Polyketides, Isoprenoids, Alkaloids
Author Leeper, Finian J., editor, Vederas, John C., editor, SpringerLink (Online service)
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Topics Chemistry, Chemistry, Organic, Biochemistry, Chemistry, Chemistry, Organic, Biochemistry, general
Publisher Springer Berlin Heidelberg
Collection folkscanomy_miscellaneous, folkscanomy, additional_collections
Language English
Book Type EBook
Material Type Book
File Type PDF
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Support Mobile, Desktop, Tablet
Scan Quality: Best No watermark
PDF Quality: Good
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Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids
Author: Dr. Finian J. Leeper, Prof. Dr. John C. Vederas
Published by Springer Berlin Heidelberg
ISBN: 978-3-540-66573-1
DOI: 10.1007/3-540-48146-X

Table of Contents:

  • Biosynthesis of Aromatic Polyketides
  • Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes
  • Biosynthesis of Prenylated Alkaloids Derived from Tryptophan
  • Tropane and Related Alkaloids
  • Biosynthesis and Metabolism of Pyrrolizidine Alkaloids in Plants and Specialized Insect Herbivores

Biosynthesis of Aromatic Polyketides — Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes — Biosynthesis of Prenylated Alkaloids Derived from Tryptophan — Tropane and Related Alkaloids — Biosynthesis and Metabolism of Pyrrolizidine Alkaloids in Plants and Specialized Insect Herbivores

This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). Volume 1 covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry

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