About this Book

The possibility of harvesting the power of electric and magnetic impulses in the

human body, commonly referred to as “neuromodulation,” is one of the most

recent and promising developments of the modern science. Since the late ´60s,

multiple invasive and non-invasive technologies have been developed and tested

in experimental and clinical settings with the final aim of modulating the function of

the central and peripheral nervous system. Clinical applications include, but are not

limited to, common neurological disorders such as Parkinson’s disease and other

movement disorders.

The bulk of evidence supporting the clinical efficacy of various invasive and

non-invasive approaches for neuromodulation has progressively led scientific

societies, patients’ associations, and regulatory entities to acknowledge the critical

role played by neuromodulation in the therapeutic algorithms of a wide range of

neurological disorders. As a result, new technologies have been recently introduced

into the market or are currently under validation. Their potential implementation into

innovative protocols for neuromodulation demands a critical revision of what are

the unmet needs for neuromodulation in movement disorders.