Monoclonal Antibodies and Immune Checkpoint Inhibitors in the treatment of Cancer

Monoclonal Antibodies and Immune Checkpoint Inhibitors in the treatment of Cancer

About this Book

Cancer is a complex disease that can evade the immune system's natural defenses. However, recent advancements in immunotherapy have revolutionized cancer treatment by using the body's own immune system to fight cancer. Monoclonal antibodies (mAbs) and immune checkpoint inhibitors are two types of immunotherapy that have shown promise in treating various types of cancer.

Monoclonal antibodies are laboratory-produced antibodies that are designed to recognize and target specific proteins on the surface of cancer cells. These antibodies can be used alone or in combination with other therapies such as chemotherapy or radiation. Monoclonal antibodies work by binding to cancer cells and blocking their ability to grow and divide, or by marking them for destruction by the immune system. For example, trastuzumab (Herceptin) is a monoclonal antibody that targets HER2-positive breast cancer cells and can be used in combination with chemotherapy to improve survival rates.

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