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Calcium Channel Blockers [electronic resource]

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Calcium Channel Blockers [electronic resource]
Original Title Calcium Channel Blockers [electronic resource]
Author Godfraind, T. (Théophile)
Publication date

Topics Medicine, Toxicology, Cardiology, Cardiology, Medicine, Toxicology
Publisher Basel : Birkhäuser Basel : Imprint : Birkhäuser
Collection folkscanomy_miscellaneous, folkscanomy, additional_collections
Language English
Book Type EBook
Material Type Book
File Type PDF
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Support Mobile, Desktop, Tablet
Scan Quality: Best No watermark
PDF Quality: Good
Availability Yes
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Calcium Channel Blockers
Author: Théophile Godfraind
Published by Birkhäuser Basel
ISBN: 978-3-0348-9599-6
DOI: 10.1007/978-3-0348-7859-3

Table of Contents:

  • Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+
  • Calcium channel blockers and calcium channels
  • The action of calcium antagonists on Ca2+ movements in isolated vessels
  • The tissue selectivity of calcium antagonists
  • Acute haemodynamic effects of calcium channel blockers
  • Calcium channels and regulation of vascular tone in hypertension
  • Long-term effects of calcium antagonists
  • Blood pressure-independent effects of calcium antagonists
  • From early clinical studies to randomized controlled clinical trials
  • Beyond the cardiovascular system

Preface — Acknowledgements — Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+ — Calcium channel blockers and calcium channels — The action of calcium antagonists on Ca2+ movements in isolated vessels — The tissue selectivity of calcium antagonists — Acute haemodynamic effects of calcium channel blockers — Calcium channels and regulation of vascular tone in hypertension — Long-term effects of calcium antagonists — Blood-pressure independent effects of calcium antagonists — From early clinical studies to randomized controlled clinical trials — Beyond the cardiovascular system — Index

The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects, and perspectives. All chapters are written by Prof. T. Godfraind, a world leading expert in the field

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