Antibodies [electronic resource] : Volume 2: Novel Technologies and Therapeutic Use | Subramanian, G

Antibodies: Volume 2: Novel Technologies and Therapeutic Use
Author: G. Subramanian
Published by Springer US
ISBN: 978-1-4613-4702-6
DOI: 10.1007/978-1-4419-8877-5

Table of Contents:

• Transgenic Technology for Monoclonal Antibody Production
• Generation, Engineering and Production of Human Antibodies Using Hucal®
• Achieving Appropriate Glycosylation During the Scaleup of Antibody Production
• Approaches to Devise Antibody Purification Processes by Chromatography
• Novel Hiv Neutralizing Antibodies Selected from Phage Display Libraries
• Monoclonal and Bispecific Antibodies in Combination with Radiotherapy for Cancer Treatment
• Antibodies, a Potent Tool to Target Genes into Designated Cells and Tissues
• Intrabodies: Development and Application in Functional Genomics and Therapy
• Expression of Recombinant Antibodies by Tumour Cells: On Road to Anti-Tumour Therapy
• Antitumor Antibodies: From Research to Clinic
• Macrophages for Immunotherapy
• Future Prospects in Antibody Engineering and Therapy

1. Transgenic technology for monoclonal antibody production -- 2. Generation, engineering and production of human antibodies using HuCAL -- 3. Achieving appropriate glycosylation during the scaleup of antibody production -- 4. Approaches to devise antibody purification processes by chromatography -- 5. Novel HIV neutralizing antibodies selected from phage display libraries -- 6. Monoclonal and bispecific antibodies in combination with radiotherapy for cancer treatment -- 7. Antibodies, a potent tool to target genes into designated cells and tissues -- 8. Intrabodies: development and application in functional genomics and therapy -- 9. Expression of recombinant antibodies by tumour cells: on road to anti-tumour therapy -- 10. Antitumor antibodies: from research to clinic -- 11. Macrophages for immunotherapy -- 12. Future prospects in antibody engineering and therapy -- Index
Volume 2: Novel Technologies and Therapeutic Use brings to the forefront current advances in novel technologies for the manufacturing of monoclonal antibodies and also their extensive clinical importance. Following on from Antibodies Volume 1: Production and Purification, this volume concentrates on: -new technologies in the manufacture of monoclonal antibodies, -the application of antibodies in cancer therapy and functional genomic therapy, -the importance of antibodies and prospects of antibody engineering for the future