Biological Matrices and Tissue Reconstruction [electronic resource]

Biological Matrices and Tissue Reconstruction
Author: Professor Dr. med. G. Björn Stark, Priv.-Doz. Dr. med. Raymund Horch, Dr. med. Eszter TÁczos
Published by Springer Berlin Heidelberg
ISBN: 978-3-642-64347-7
DOI: 10.1007/978-3-642-60309-9

Table of Contents:

• Wound Healing in Surgery
• Influence of Collagen Membranes and Collagenous Sponge Material in the Connective Tissue Matrix During Wound Healing: An Immunohistochemical Study
• Collagen Matrix Implantation for Tissue Repair and Wound Healing: Present and Perspectives
• Characterization of Biomaterials for Tissue Repair
• Properties of Different Tissue Sealants
• Genetically Modified Fibroblasts-Fibrin-Glue-Suspension for in vivo Drug Delivery of Epidermal Growth Factor (EGF): A Surface Gene Therapy Model not only for Wounds
• Genetically Modified Fibroblasts Induce Angiogenesis in the Rat Epigastric Island Flap
• Stimulation of Growth and Proliferation of Human Cultured Keratinocytes by KGF-transfected Cells in vitro
• Genetically Modified Human Keratinocyte Clone Secretes EGF
• Fibrin Glue as a Carrier for Cultured Human Keratinocytes versus Cultured Epidermal Skin Grafts in Athymic Mice Full-thickness Wounds
• Enhanced Expression of Integrin Receptors During Proliferation of Activated Keratinoblasts Prepared for Transplantation as Cell Suspension in Fibrinous Matrix
• Autologus ORS-Keratinocytes in the Therapy of Chronic Leg Ulcers
• Transplantation of Autologous Cultured Urothelium Cells onto a Prefabricated Capsule in Rats
• Urothelial Cell Culture Behavior in Fibrin Glue Compared to Conventional Culture Medium
• Autologouos Transplantation of Urothelium into Demucosalized Gastrointestinal Segments
• Co-cultured Human Liver Epithelial Cells in Collagen Gel: A Source for Tissue Engineering in Vitro
• Clinical Use of Autologous Endothelial Cell-Seeded PTFE Vascular Grafts for Coronary Artery Revascularization
• Influence of Fibrinogen Adhevises and their Components on Growth and Attachment of Human Endothelial Cells
• The Effect of Long-term Culture on the Ability of Human Auricular Chondrocytes to Generate Tissue Engineered Cartilage
• Tissue Engineered Cartilage with Cultured Chondrocytes and a Collagen Sponge Matrix

From the contents: Tissue Engineering of Skletal Muscle Using Micropatterned Biomaterials -- Chondrocyte-Differentiation in Fibrin-Coating on Polytetrafluorethylene-Membranes -- Wound Healing in Surgery -- Delivery Systems for Osteoinductive Proteins -- The Role of Fibrin Glue as Provisional Matrix in Tendon Healing -- Autologous ORS-Keratinocytes in the Therapy of Chronic Leg Ulcers -- Transplantation of Autologous Cultured Urothelium Cells onto a Prefabricated Capsule in Rats
Tissue Engineering, just leaving its egg shells behind may well evolve to a major breakthrough in medicine. Progress in material engineering and biology have made it imaginable in short time to replace lost tissue functions and even lost body parts without the artificial and supply problems of transplantation. In a workshop symposium organized by the European Tissue Repair Society in August 1997 leading scientists from engineering, basic sciences and medicine contributed to this book, which specially stresses the importance of matrix materials for tissue reconstruction and wound healing. Starting with skin, an increasing number of groups is rapidly developing substitutes for most tissues which soon will enter clinical practice